I'm currently on Alcalabrutinib (Calquence) for CLL. All my bloodwork shows I'm in normal ranges for WBC, RBC, Hemoglobin, as well as other indicators and am considered in remission for 6 months. I've had both Pfizer vaccine shots 60 days ago with no side effects or issues. After an antibodies test 4 weeks after my second shot, my specialist claims my efficacy is 'less than robust' against COVID 19. Test results were: Anti-SARS-CoV-2 Spike Protein IgG Index: 0.02 S/CO std range: 0.00 -… read more
So, since my post 6 mos ago, I still have no antibodies. I have learned that taking oral drugs like Imbruvica and Calquence for CLL causes the vaccines to become virtually ineffective. Even had the booster in August as soon as it was available. In September I contracted Covid from a golf outing in Indiana (no mask or vaccine mandate state). My oncologist ordered the Monoclonal antibodies infusion for me immediately. I came out of it ok and feel great today, though I'm told I still likely have no effective antibodies. Still masking indoors but not for outdoor activities or with family. So far, so good.
Latest test (9/20) still high for antibodies.
I’m now being tested monthly for antibodies (getting tested today) in order to determine the need for a booster shot. I believe the additional Moderna shots I received in April and May after testing low with the Pfizer shots acted in the same way a booster does so we’ll see how long this high response continues. Once again I’m not currently on any treatment for my CLL.
You say, “they want me to get the vaccine.” If by “they” you mean your doctor(s), then follow their advice.
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