Busulfan is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat chronic myelogenous leukemia (CML). Busulfan is often combined with other drugs such as Cytoxan and Fludara in chemotherapy regimens. Busulfan is marketed under the brand names Myleran and Busulfex.
Busulfan is an anticancer drug used in chemotherapy. Busulfan is a member of a class of drugs called alkylating agents. Busulfan is believed to work by preventing the production of DNA in cells, thereby blocking cell division.
How do I take it?
Busulfan can be administered as an intravenous infusion or taken orally.
Common side effects of Busulfan include nausea, vomiting, diarrhea, mouth sores, loss of appetite, infections, low blood counts, electrolyte abnormalities and infertility.
Serious side effects of Busulfan include liver damage, lung damage, seizures, fetal harm, and problems with the adrenal glands. Some side effects, such as lung damage and increased risk for some types of cancer, can occur years after treatment with Busulfan has stopped.
For more details about this treatment, visit:
Busulfan — Chemocare
Chemotherapy for Chronic Myeloid Leukemia — American Cancer Society