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The Cytoxan brand name has been discontinued in the U.S. for reasons unrelated to safety or efficacy. Other brand names or generic alternatives may be available. If you’re currently taking this medication, talk to your healthcare provider about safe options for transitioning to a different treatment.

Overview

Cytoxan was a prescription medication approved by the U.S. Food and Drug Administration (FDA) for treating cancers including acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL), and chronic myelocytic leukemia (CML). Cytoxan was often combined with other drugs and corticosteroids in chemotherapy regimens. Cytoxan was also known by its drug name, cyclophosphamide. 

Cytoxan was an anticancer drug used in chemotherapy. Cytoxan was a member of a class of drugs called alkylating agents. Cytoxan was believed to work by preventing the production of DNA in cells, thereby blocking cell division.

Limitations of Cytoxan use included its safety and effectiveness for nephrotic syndrome treatment in adults and other renal diseases. 

How was it taken?

Cytoxan was administered as an intravenous infusion, taken orally, or injected into muscles.

Side effects

Common side effects of Cytoxan included nausea, vomiting, temporary hair loss, darkening of the skin and nails, loss of appetite, fatigue, increased risk for infection, and anemia.

Serious side effects of Cytoxan included the risk of permanent infertility in both men and women and increased risk for some types of cancer, even years after treatment has stopped. Rarely, Cytoxan may cause serious heart problems.

For more details about this treatment, visit:

Cytoxan (Oral, Intravenous) — Drugs.com

 

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