Novantrone (Mitoxantrone) for Leukemia | MyLeukemiaTeam

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Novantrone is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat acute nonlymphocytic leukemia (ANLL) in adults. Novantrone is also known by its drug name, mitoxantrone. The brand name Novantrone is discontinued in the U.S. Generic forms may be available.

Novantrone is an antineoplastic drug. Novantrone is believed to work by disrupting synthesis and repair of DNA in cells.

How do I take it?
Novantrone is administered as an intravenous infusion during chemotherapy treatment.

Side effects
The FDA-approved label for Novantrone lists common side effects including headache, tiredness, frequent infections, depression, hair loss, runny nose, nausea, vomiting, diarrhea, heartburn, stomach pain, changes in the menstrual cycle, abnormal bleeding, low blood cell counts, and temporary blue-green discoloration of the urine or whites of the eyes.

Rare but serious side effects listed for Novantrone can include congestive heart failure and severe skin damage at the injection site.

For more details about this treatment, visit:

Novantrone — RxList

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