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Real members of MyLeukemiaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
August 19, 2024
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MyLeukemiaTeam

Certainly! Here are some molecular factors involved in diagnosing Chronic Lymphocytic Leukemia (CLL):

- Gene Mutations: Specific genes like TP53 and IgVH are often mutated in CLL cells. Identifying these mutations helps understand the prognosis
- Cytogenetic Tests: Tests like fluorescence in situ hybridization (FISH) and Show Full Answer

Certainly! Here are some molecular factors involved in diagnosing Chronic Lymphocytic Leukemia (CLL):

- Gene Mutations: Specific genes like TP53 and IgVH are often mutated in CLL cells. Identifying these mutations helps understand the prognosis.
- Cytogenetic Tests: Tests like fluorescence in situ hybridization (FISH) and gene mutation tests identify gene abnormalities within CLL cells.
- Serum Immunoglobulin Tests: These tests measure antibody levels, which are often low in CLL due to cancerous B cells not making immunoglobulin properly.

These molecular factors help doctors differentiate between types of leukemia and estimate prognosis.

August 19, 2024
A MyLeukemiaTeam Member

Thank you, Robert507. I have been frustrated by some outdated information and lack of information about the medication I am about to take, which is Brukinsa, other than on its own site.

August 19, 2024
A MyLeukemiaTeam Member

We know that there are many different white blood cells. I never got a good answer from my doctor except "looks good?" I like to focus on the "T" and "B" cells. The B cells mark cells to be attacked by the T cells. I currently take medication to inactivate B and may be T cells. I have no il affects from the medication and my WBC count is 6900. I understand the biological and chemical reaction "BTK Inhibitor" response by the medication. I think we are in the 21st century and there are many medications for the many different types of leukemias. Some of the RESOURCE information is dated with incomplete answers for new treatments listed after 2020? My treatment was FDA approved 12/22 so it may or may not be listed in some articles?

August 19, 2024

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