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I am 61 years old. I was diagnosed with AML M0, M1 on 11.10.2017. Which type of AML does M0, M1 fall into?

A MyLeukemiaTeam Member asked a question 💭
Turkey,Hatay,İskenderun

On 11.10.2017, I received 1 course of chemotherapy with the diagnosis of AML M0, M1. The FLT gene mutation test came back negative. Initially, there were 33% blast cells in my bone marrow. After 1 course, I went into complete remission. On 21.12.2017, I received a stem cell transplant from my older brother. I stayed in complete remission for 3 years and 5 months. At the end of this period, since the platelet counts were gradually decreasing (to 33,000), a bone marrow aspiration showed that the… read more

November 14, 2024
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MyLeukemiaTeam

Based on the information provided:

- AML M0: Undifferentiated acute myeloblastic leukemia. The cells in the bone marrow are immature white blood cells (called blast cells or myeloblasts) but do not possess specific changes found in other groups
- AML M1: Acute myeloblastic leukemia with minimal maturation. Myeloblasts Show Full Answer

Based on the information provided:

- AML M0: Undifferentiated acute myeloblastic leukemia. The cells in the bone marrow are immature white blood cells (called blast cells or myeloblasts) but do not possess specific changes found in other groups.
- AML M1: Acute myeloblastic leukemia with minimal maturation. Myeloblasts have small signs of cancerous changes, including overgrowth of some immature white blood cells.

Your diagnosis of AML M0 and M1 falls into the French-American-British (FAB) classification system for AML, which categorizes AML into subtypes M0 through M7 based on the type of white blood cell involved and the stage of maturity of the cells.

Timeline of your treatment and remission:
- 11.10.2017: Diagnosed with AML M0, M1; received chemotherapy.
- 21.12.2017: Received a stem cell transplant from your older brother.
- 3 years and 5 months later: Relapse detected due to decreasing platelet counts.
- Videza treatment: Initially did not reduce blast cell count.
- Videza + venetoclax treatment: Achieved remission again but required platelet and neofogen injection support.
- 18.04.2023: Second stem cell transplant from your brother.
- Current status: In remission for 18 months, back to work for 8 months.

Your journey highlights the importance of continuous monitoring and personalized treatment plans in managing AML.

November 14, 2024

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