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Diagnosis MDS-IB2

January 6, 2025
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A MyLeukemiaTeam Member

MDS can progress to AML. I am in Cycle 26 of treated at UCLA and have Azacitidine Injections and Venetoclax pills. This treatment was originally approved for AML and recently for MDS. The treatment can be the same. Being treated at MD Anderson is excellent. Like UCLA it is a "Center of Excellence" in relation to cancer. Fortunately, you are young enough to be considered for a stem cell procedure. Currently, what is your treatment for MDS.

The best to you.

Alan

January 7, 2025
A MyLeukemiaTeam Member

Jeff, I also had MDS, subtype EB2 and it has since progressed to AML. From everything I’ve read, MDS, subtype EB2 is high risk for progressing to AML.

January 16, 2025
A MyLeukemiaTeam Member

Thank you Alan, I'm already in treatment and just finishing my first cycle of chemotherapy in a clinical trail at MD Anderson.
My curiosity in the question is it's just a few percentage point difference in blast count between MDS-IB2 and AML.
In this trial, the treatment is the same for either, with stem cell replacement being the goal for cure.
I appreciate your help.

January 6, 2025
A MyLeukemiaTeam Member

Jeff,

There is a difference between "diagnosis and treatment". MDS-EB2 is a diagnosis that relates to the number of blasts cells in your bone marrow. MDS-EB2 is not AML. The ICD -10-CM diagnostic billing code for MDS is D46-Z (https://icdlist.com/icd-10/d46z). The ICD code is for diagnostic and treatment billing to your insurance company and/or Medicare.

I suggest you obtain copies of your blood tests (CBC & CMP) plus Aspirate and Bone Marrow Procedure(s) from your medical provider.

Alan

https://icdlist.com/icd-10/d46z
January 6, 2025
MyLeukemiaTeam

It seems you're referring to MDS-EB2, which is indeed a subtype of myelodysplastic syndrome (MDS). According to my knowledge base, MDS-EB2 is characterized by a higher percentage of blast cells in the bone marrow (10%-19%) or blood (5%-19%). This subtype is considered high-risk and has a greater chance of progressing to Show Full Answer

It seems you're referring to MDS-EB2, which is indeed a subtype of myelodysplastic syndrome (MDS). According to my knowledge base, MDS-EB2 is characterized by a higher percentage of blast cells in the bone marrow (10%-19%) or blood (5%-19%). This subtype is considered high-risk and has a greater chance of progressing to acute myeloid leukemia (AML). If you feel your diagnosis isn't being addressed in certain resources, it may be worth discussing with your healthcare provider for tailored guidance.

January 6, 2025

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