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A MyLeukemiaTeam Member asked a question 💭
Corbin, KY

I have cll, at my most recent bloodwork I had 2% blast. My doctor was reading off results and seem pleased, until she got to the blast. Suddenly her tone changed and she wanted me to come back in six weeks for more bloodwork. I’m trying not to stress over this, but find it concerning. Has anyone else experienced the sudden appearance of blast with cll?

September 10, 2025
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A MyLeukemiaTeam Member

The issue with our illness is that the cells are not correct. Your defect seems to be cells released before they are mature to function correctly. The "B" cells job is to mark cells to be attacked. If your blast cells are "B" cells then they are not doing their job. The blast cells could be red blood cells then you will be lacking cells to carry oxygen. I think you should ask your medical people to answer which type of cell is being released? Will the cell mature? Will this immature cells cause problems? The percentage of blast cells in the sample and the degree of illness possible? I think you can research about blast cells and come up with more questions. If your medical people are "share and care" you will get answers. If your people are "watch & wait" you will not be getting a lot of answers. Celebrating Long Life (CLL)

September 10, 2025
A MyLeukemiaTeam Member

This is what i got when i added your data to chatgpt :-) Hope this helps!
What "Blasts" Are
Blasts are very immature white blood cells (precursors to lymphocytes, neutrophils, etc.).

Normally, blasts are only found in the bone marrow — they should be <1% in peripheral blood.

If blasts show up in the blood, it can signal that the bone marrow is releasing immature cells.

📊 2% Blasts in CLL

CLL is a mature B-cell leukemia — so blasts are not normally elevated in CLL.

A 2% blast count in blood is slightly above normal and can mean:

Mild marrow stress or recovery (sometimes happens after infection, treatment, or marrow regeneration)

Early sign of progression — in rare cases, CLL can transform into a more aggressive leukemia/lymphoma (like Richter’s transformation or acute leukemia), which often shows higher blasts.

Lab variation — 1–2% can sometimes be seen transiently and not be clinically significant.

⚠️ When It’s Concerning

Doctors usually start worrying when:

Blasts are >5% in blood (or >20% in bone marrow — which defines acute leukemia)

There are new symptoms (rapidly enlarging lymph nodes, fever, night sweats, weight loss)

Blood counts change suddenly (drop in platelets, hemoglobin, or very rapid rise in WBCs)

✅ What You Should Do

Share this result with your hematologist/oncologist.

They may repeat the test or order a flow cytometry or bone marrow biopsy if there are other concerning signs.

If you are feeling well and your other counts are stable, a single 2% reading may just be monitored.

September 10, 2025

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