Does an enlarged spleen and high white blood cells mean CMML has progressed to AML?
Not necessarily. An enlarged spleen and high white blood cell counts can occur in CMML itself without progression to AML.
People with MP-CMML (the myeloproliferative type) often have high levels of blood cells and commonly experience an Show Full Answer
Does an enlarged spleen and high white blood cells mean CMML has progressed to AML?
Not necessarily. An enlarged spleen and high white blood cell counts can occur in CMML itself without progression to AML.
People with MP-CMML (the myeloproliferative type) often have high levels of blood cells and commonly experience an enlarged spleen as part of their CMML, not as a sign of progression.
However, people with MP-CMML are more likely to develop AML over time. About 63 percent of people with type 2 CMML are diagnosed with AML within five years.
To determine if CMML has progressed to AML, doctors look at the percentage of blast cells (immature blood cells) in your blood and bone marrow. AML is diagnosed when blasts make up more than 20 percent of the blood and bone marrow.
If you're concerned about progression, talk with your doctor about checking your blast cell levels through blood tests and bone marrow analysis. They can give you a clearer picture of where things stand with your condition.
February 10
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