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Real members of MyLeukemiaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I'm out of remission for the third time. This is the worst it's been. I feel good,but I'm just too tired. After my oncologist app Tues,she d

A MyLeukemiaTeam Member asked a question 💭

ecided on targeted therapy instead of chemo. I'll b taking Acalabrutinib,daily until disease progression. Has anyone had this? How'd it work for you?I'm very overwhelmed.

April 9
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Reactions
A MyLeukemiaTeam Member

Thank you so very much for your replies. It really helps a lot that others care. I'm feeling better about this today,I will put my faith in God,n my Dr,who never steered me wrong. I appreciate you all. Have a great weekend.

April 10
MyLeukemiaTeam

How has acalabrutinib worked for others with leukemia who've experienced relapse?

It's completely understandable to feel overwhelmed, especially after going through this multiple times. The fatigue you're experiencing is a common symptom, and many people find that targeted therapies can be easier on the body than Show Full Answer

How has acalabrutinib worked for others with leukemia who've experienced relapse?

It's completely understandable to feel overwhelmed, especially after going through this multiple times. The fatigue you're experiencing is a common symptom, and many people find that targeted therapies can be easier on the body than traditional chemotherapy.

Acalabrutinib is a targeted therapy that's been shown to be effective for certain types of leukemia. In clinical studies, people taking acalabrutinib in combination with other medications had better outcomes than those on standard chemotherapy, with fewer deaths reported.

The most common side effects people experienced included:
* Low white blood cell count (neutropenia)
* Headache
* Diarrhea
* Muscle and bone pain
* Infections

Because targeted therapies work differently than chemotherapy—attacking specific cancer cells rather than all fast-growing cells—they often cause fewer side effects. Many people are able to take these medications as daily pills and continue with their regular activities.

Your doctor will monitor you regularly with blood tests to see how well the treatment is working. Some people stay on targeted therapy for extended periods while maintaining good quality of life.

It's important to communicate openly with your healthcare team about any side effects or concerns. They can help adjust your treatment plan if needed.

April 9
A MyLeukemiaTeam Member

I tell people all of the time that we first trust God, then the doctors that He puts in our lives, and then our support groups. We can not go wrong if we just stay the course.

April 10
A MyLeukemiaTeam Member

I have been tking Brukinsa for over 2 years. Yesterday I was at the gym for an hour and today I cut weeds for 90 minutes. Each time I was breathing excessively from my effort and after 20 minutes of relaxing I was ready to go again? I think I have this fatigue thing but it seems to go away after I relax? I also never had chemo since I consider those drugs toxic. I hope your can be as healthy and happy as I seem to be today.

April 9
A MyLeukemiaTeam Member

It targets the cancer cells only,not all cells like chemo does

April 9

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