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Real members of MyLeukemiaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
May 5
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MyLeukemiaTeam

Bone and joint pain after CLL treatment is a well-recognized side effect, and it's great that you're in remission! Even after treatment ends, some people continue to experience lingering discomfort.

Both venetoclax and ibrutinib are known to cause muscle and bone pain during and after treatment. A MyLeukemiaTeam member Show Full Answer

Bone and joint pain after CLL treatment is a well-recognized side effect, and it's great that you're in remission! Even after treatment ends, some people continue to experience lingering discomfort.

Both venetoclax and ibrutinib are known to cause muscle and bone pain during and after treatment. A MyLeukemiaTeam member shared that joint pain from targeted therapies "comes and goes" and can sometimes be severe enough to affect mobility. Here are some things worth knowing about long-term bone pain after CLL treatment:

- Targeted therapies like venetoclax and ibrutinib are linked to ongoing muscle and bone pain even after treatment
- Bone marrow recovery takes time after treatment, which can contribute to lingering discomfort
- Pain patterns can vary — some people experience it occasionally, others more persistently

It's really important to let your care team know about any ongoing bone pain. They can help rule out other causes and suggest ways to manage it, whether through medication, physical therapy, or other supportive care options.

May 5

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