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A MyLeukemiaTeam Member asked a question πŸ’­
Perth, AU

When I finished my Chemotherapy in 2022 it was discovered that I had an immunoglobulin deficiency. It would appear that the chemo had destroyed my immune system
There are three parts to the bloods within the immunoglobulin, IVG, IVM and IVA. For me IVM and IVA no longer exist the chemo has wiped them out. The IVG issue made me have therapy once a month to raise the blood levels, unfortunately this is ongoing and the levels for IVG are like waves, they come up with treatment but drop over the… read more

September 10 (edited)
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MyLeukemiaTeam

Thank you for sharing your experience so thoroughly β€” it will absolutely help others going through similar challenges. This is a really important topic for people with leukemia post-chemotherapy.

Chemotherapy can damage the bone marrow's ability to produce healthy blood cells, including the white blood cells responsible Show Full Answer

Thank you for sharing your experience so thoroughly β€” it will absolutely help others going through similar challenges. This is a really important topic for people with leukemia post-chemotherapy.

Chemotherapy can damage the bone marrow's ability to produce healthy blood cells, including the white blood cells responsible for immune function. When immunoglobulin levels drop, the body becomes far more vulnerable to infections β€” as a MyLeukemiaTeam member experienced firsthand with two bouts of pneumonia in a single year. 1. How long does IVG therapy typically continue?

For many people, immunoglobulin replacement therapy becomes a long-term or ongoing commitment when the immune system doesn't fully recover after chemotherapy. The "wave" pattern β€” levels rising after treatment then dropping before the next visit β€” is a well-known challenge and is exactly why consistent, regular infusions are necessary. 2. Alternatives or adjustments to IVG therapy

It's worth having a detailed conversation with your specialist about the following options:

- Subcutaneous immunoglobulin (SCIG) β€” administered under the skin, often at home, in smaller but more frequent doses, which can help smooth out those level fluctuations
- Adjusted infusion frequency β€” some people benefit from more frequent but smaller IVG doses to maintain steadier levels
- Prophylactic antibiotics β€” sometimes used alongside immunoglobulin therapy to further reduce infection risk

Always discuss any changes with your hematologist before adjusting your current treatment plan. 3. Supporting your immune system

While nothing replaces medical treatment, there are some supportive steps that may help:

- Vaccinations β€” staying current on recommended vaccines is important, though timing matters; doctors often recommend getting vaccinated when immune levels are at their strongest, such as shortly after an infusion
- Sleep and stress management β€” both have a meaningful impact on immune function
- Balanced nutrition β€” a nutrient-rich diet supports overall health
- Continuing your protective habits β€” masking in public and avoiding people who are unwell are genuinely effective strategies, as you're already doing

The precautions already being taken are exactly the right approach. Staying vigilant is not overcautious β€” it's smart.

September 10

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A MyLeukemiaTeam Member asked a question πŸ’­
Pittsburgh, PA

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