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Real members of MyLeukemiaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyLeukemiaTeam Member asked a question 💭
Sydney, AU
March 15, 2025
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A MyLeukemiaTeam Member

Hi, Robert, SLL and CLL are the same condition. How it's labeled depends on where the bad cells are located.
As Copilot put it: "Small Lymphocytic Lymphoma (SLL) and Chronic Lymphocytic Leukemia (CLL) are essentially the same disease, but they are classified differently based on where the cancer cells are found.

CLL: Diagnosed when most cancer cells are in the blood and bone marrow.
SLL: Diagnosed when most cancer cells are in the lymph nodes.

Both conditions involve abnormal B lymphocytes, a type of white blood cell, and are treated similarly. They are slow-growing cancers and are often considered different stages or manifestations of the same underlying disease."

March 21, 2025
A MyLeukemiaTeam Member

My doctor first told me I had SLL or CLL. Then months later he changed to CLL? So I would say time will determine what the verdict will be in the future. I think we all have lots of time since this illness is not a fast acting bad agent inside the body most of the time.

March 21, 2025
MyLeukemiaTeam

CLL and SLL are actually the same condition, just found in different places in your body. When the cancer cells are mainly in your blood and bone marrow, doctors call it CLL. When the cancer cells are mostly in your lymph nodes, they call it SLL.

Both conditions are caused by abnormal lymphocytes (a type of white blood Show Full Answer

CLL and SLL are actually the same condition, just found in different places in your body. When the cancer cells are mainly in your blood and bone marrow, doctors call it CLL. When the cancer cells are mostly in your lymph nodes, they call it SLL.

Both conditions are caused by abnormal lymphocytes (a type of white blood cell). In over 95% of cases, the specific cells affected are B lymphocytes or B cells. Treatment options have evolved significantly over the past 20 years. While traditional chemotherapy was once standard, there are now many new targeted therapies available that are often more effective and easier to tolerate. Many of these newer treatments can even be taken as pills at home rather than requiring clinic visits for IV treatment.

Some people may not need immediate treatment and can follow a "watchful waiting" approach with regular monitoring through blood tests and doctor visits. The key is staying in close communication with your healthcare team and reporting any new or changing symptoms.

March 15, 2025

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