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Real members of MyLeukemiaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyLeukemiaTeam Member asked a question 💭
Sierra Vista, AZ
June 12, 2025
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A MyLeukemiaTeam Member

This Feburary I think I had the flu? I was at 6,900 and increased to 13,000. Today I am at 7,100? I have only been medicated for 16 months so I will worry at 3 to 5 years when the cells mutate and control is lost? This is what others call relapse? The good thing is that many different medications use differnet means to control the bad cells so control can be accomplished until the cells mutate again and control is lost.

June 15, 2025
MyLeukemiaTeam

Yes, relapses can occur with CLL. The disease progression and treatment needs vary between individuals, with some having indolent (slow-growing) CLL that may not require immediate treatment, while others experience more aggressive forms requiring prompt intervention.

Your doctor can help predict the likelihood of disease Show Full Answer

Yes, relapses can occur with CLL. The disease progression and treatment needs vary between individuals, with some having indolent (slow-growing) CLL that may not require immediate treatment, while others experience more aggressive forms requiring prompt intervention.

Your doctor can help predict the likelihood of disease progression or relapse using the CLL International Prognostic Index (CLL-IPI), which considers factors like:
- Specific gene mutations
- CLL stage
- Age
- Certain protein levels (like ZAP-70 or CD38)
- Beta-2 microglobulin levels If you're concerned about relapse, watch for these common symptoms:
- B symptoms (night sweats, unexplained fever, weight loss)
- Increased fatigue
- Shortness of breath
- Swollen lymph nodes
- Feeling full after eating small amounts
- Frequent infections

Regular monitoring through blood tests and check-ups with your healthcare team is essential for tracking any changes in your condition.

June 12, 2025
A MyLeukemiaTeam Member

I did not know the mutate again is why we end up needing another treatment. Thank you for that

June 21, 2025

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