TP53 is a gene that, when changed or mutated, can affect how cancer cells grow and divide. About 50% of people with certain types of leukemia have changes in the TP53 gene. These changes can impact how well certain treatments work.
When doctors talk about D13 (chromosome 13) deletion, they're referring to a missing piece Show Full Answer
TP53 is a gene that, when changed or mutated, can affect how cancer cells grow and divide. About 50% of people with certain types of leukemia have changes in the TP53 gene. These changes can impact how well certain treatments work.
When doctors talk about D13 (chromosome 13) deletion, they're referring to a missing piece of chromosome 13. This occurs in approximately 25% of some leukemia cases. Like TP53 mutations, chromosome 13 deletions can affect how cancer cells behave. It's important to note that if you have these genetic changes, it may affect your treatment options. For example, some forms of leukemia with TP53 mutations don't respond as well to traditional chemotherapy. In such cases, your doctor might recommend different treatment approaches, such as targeted therapies or clinical trials.
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