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Real members of MyLeukemiaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
September 17, 2025
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MyLeukemiaTeam

Yes, this is good news! The absence of TP53 alterations and chromosome 17p deletions is a positive finding. These genetic changes are typically associated with poorer outcomes and treatment resistance in CLL/SLL patients. Not having these mutations means you're more likely to respond better to traditional treatments Show Full Answer

Yes, this is good news! The absence of TP53 alterations and chromosome 17p deletions is a positive finding. These genetic changes are typically associated with poorer outcomes and treatment resistance in CLL/SLL patients. Not having these mutations means you're more likely to respond better to traditional treatments. Patients without these genetic changes generally have more treatment options available to them. While those with TP53 or 17p deletions often need to use specific targeted therapies, you may be eligible for a broader range of treatment approaches. This gives your healthcare team more flexibility in designing your treatment plan.

September 17, 2025

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