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What do the numbers in your HLA typing report mean?

HLA (Human Leukocyte Antigen) typing identifies specific markers on your cells that help determine compatibility for stem cell transplantation. The letters (A, B, C, DRB, DQA1) represent different HLA gene groups, and the numbers after them (like 26:01 or 29:02) identify Show Full Answer

What do the numbers in your HLA typing report mean?

HLA (Human Leukocyte Antigen) typing identifies specific markers on your cells that help determine compatibility for stem cell transplantation. The letters (A, B, C, DRB, DQA1) represent different HLA gene groups, and the numbers after them (like 26:01 or 29:02) identify specific variants of those genes.

You inherit half of your HLA markers from each parent. The closer your HLA markers match your donor's markers, the better chance the transplant has of being successful. How closely the HLA cells match between donor and recipient is one of the most important factors in transplant success.

It's actually normal for your numbers to differ from a potential donor's numbers - that's what the matching process is all about. Finding someone who matches well enough across the key HLA markers is the goal. Biological siblings have a 1 in 4 chance of having the same HLA type, and only 25 to 35 percent of people have a sibling who is an HLA match.

The good news is that with unrelated donors, there are far more options available, which increases your chance of finding a good match compared to relying only on family members.

Your care team will evaluate how well potential donors match your specific HLA profile to find the best option for you.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

Stem Cell Transplants for Leukemia