What would you like to know about chronic myelomonocytic leukemia (CMML)?
CMML is a rare type of blood cancer that develops from monocytes, which are white blood cells that help fight infection. In CMML, the body makes high levels of abnormal, immature monocytes that don't work properly and crowd out healthy blood cells.
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What would you like to know about chronic myelomonocytic leukemia (CMML)?
CMML is a rare type of blood cancer that develops from monocytes, which are white blood cells that help fight infection. In CMML, the body makes high levels of abnormal, immature monocytes that don't work properly and crowd out healthy blood cells.
About 1,100 people are diagnosed with CMML each year in the United States. It's more common in older adults (about 90 percent are at least 60 years old) and men are twice as likely to develop it as women.
Key facts about CMML:
- It develops from different cells than CML and requires different treatments
- It shares characteristics with both myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPNs)
- It's classified into subtypes (0, 1, and 2) based on the percentage of blast cells in blood and bone marrow
Common symptoms can include:
- Weakness or tiredness
- Easy bruising or bleeding
- Frequent infections
- Enlarged spleen or liver
- Night sweats
- Bone pain
- Unintentional weight loss
Would you like more specific information about diagnosis, treatment options, or prognosis for CMML?
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diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.
Chronic Myelomonocytic Leukemia: An Overview
November 12, 2025