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Hello Annette4. I started IVIG (immunoglobulin) in Nov 2024. I kept getting sinus crap and my IgG was checked. The acceptable bottom number is 650 and my hematologist said they get concerned when below 500. Mine had tanked to 250. First round was every 28 days, then 42 days, then one 53 and last one in October was 60 days. IgG was going down slowly when on 42 and 53 day cycle. October it was 461 so my next IVIG is 12/4 or 42 days and another in Jan. Any treatment affects the immune system. After the Calquence was stopped in June 2025, blood work in August for MDR(?) measured 6.7% of CLL still in bone marrow. So remission but not cured. I don't think there is a cure, just maintenance and monitor. I hope this helps and I know the infusions will help keep your immune system working properly.
What is the purpose of continuing immunotherapy monthly after chemotherapy for CLL in remission?
Continuing immunotherapy after completing chemotherapy is a common approach for CLL treatment. The immunotherapy helps maintain your remission by targeting any remaining leukemia cells that chemotherapy may have missed.
Thank you.
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