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Real members of MyLeukemiaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyLeukemiaTeam Member asked a question 💭
Australia
March 25
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Can systemic mastocytosis cause liver damage?

Yes, systemic mastocytosis can cause liver damage. When mast cells collect in organs, including the liver, they can lead to organ damage and dysfunction.

One of the signs of systemic mastocytosis is hepatomegaly, which means an enlarged liver. This occurs because mast cells Show Full Answer

Can systemic mastocytosis cause liver damage?

Yes, systemic mastocytosis can cause liver damage. When mast cells collect in organs, including the liver, they can lead to organ damage and dysfunction.

One of the signs of systemic mastocytosis is hepatomegaly, which means an enlarged liver. This occurs because mast cells build up in the liver tissue.

Doctors look for what are called "C findings" to identify organ damage from systemic mastocytosis. These findings include:

* Decreased liver function
* Altered blood cell counts
* Weight loss
* Bone lesions (soft spots)

If mast cell leukemia causes organ damage, it may be classified as acute MCL (aMCL). When there's no organ damage present, it's called chronic MCL (cMCL).

It's important to work closely with your healthcare team to monitor liver function and manage any complications that arise from systemic mastocytosis.

March 25

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