It sounds like you're asking about the difference between CMML and other types of leukemia — totally understandable, since the names can sound very similar and confusing!
CMML (Chronic Myelomonocytic Leukemia) is a rare blood cancer that develops from monocytes, which are white blood cells that help your immune system fight Show Full Answer
It sounds like you're asking about the difference between CMML and other types of leukemia — totally understandable, since the names can sound very similar and confusing!
CMML (Chronic Myelomonocytic Leukemia) is a rare blood cancer that develops from monocytes, which are white blood cells that help your immune system fight infection. In CMML, the body produces too many immature, abnormal monocytes that don't work properly and crowd out healthy blood cells. CMML is not the same as CML (Chronic Myeloid Leukemia). Here's how they differ:
- Cell origin: CMML develops from monocytes; CML develops from different cells entirely
- Gene changes: Each is caused by different genetic mutations
- Treatment: They require different therapies
- Progression: CML has three distinct phases (chronic, accelerated, and blast); CMML has subtypes based on blast cell percentages CMML itself has two main subtypes based on white blood cell (WBC) levels:
- MD-CMML (dysplastic): Low or normal WBC levels; generally associated with a more positive outlook
- MP-CMML (proliferative): High WBC levels; can cause symptoms like an enlarged spleen, night sweats, and bone pain
Knowing your subtype helps guide treatment decisions and gives you a better picture of what to expect. It's worth asking your doctor which subtype you have if you haven't already!
October 24
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