I had a SCT (from my sister’s cells) in June 2020 for AML, relapsed in June 2021; and have been receiving chemotherapy treatments since, most recently for widespread extramedullary disease, including a month of inpatient hospitalization in May. We’ve agreed that a second stem cell transplant, this time from an unrelated donor, should happen. Have any of you had a second transplant, and how was it different from your first? I know the chemo will be reduced intensity.
I wish you the best with your second transplant. I have not and hope I never need a second one. I had a transplant 3 years ago with my sister as the donor. I have been well except for some mild GVHD issues. Is it thought that your relapse was due to having a related donor? Sending you positive thoughts and prayers for a successful transplant.
Thank you for your answer. I wish you all the best with your second transplant.
Thank you, Patricia. My transplant doctor believes that my complete lack of GVHD meant that my sister was in some ways too good a match, and that my body did not mount an adequate immunological defense, weakening the graft. At least that’s my limited understanding. He’s chosen an unrelated donor this time around in the hopes of a better outcome.
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