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I am newly diagnosed with CLL, mutated IgHv, with 13q deletion. I have an elevated LDH. What dies this mean for prognosis and treatment?

A MyLeukemiaTeam Member asked a question 💭
Albuquerque, NM
May 26, 2024
 · 
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A MyLeukemiaTeam Member

Hi Zwanet. Following is a link regarding some information on your LDH being high. As you can see, there are numerous things that it may or may not be. I would give your primary or your oncologist a call and get their input. Never hesitate to ask them questions. I'm not positive, but I do not think it is used/or part of ones prognosis. But again, ask your doctor ok. Let us know what they say:):)
https://my.clevelandclinic.org/health/diagnosti...

LDH (Lactate Dehydrogenase) Test: What It Is & Results
LDH (Lactate Dehydrogenase) Test: What It Is & Results
https://my.clevelandclinic.org/health/diagnostics/22736-lactate-dehydrogenase-ldh-test
May 26, 2024
MyLeukemiaTeam

Based on the context provided:

### Prognosis
- Mutated IGHV Gene: Generally associated with a better prognosis. People with this mutation often have more effective treatment responses and longer survival rates.
- 13q Deletion: This is considered a favorable prognostic factor, indicating a better outlook.
- Elevated LDH: Show Full Answer

Based on the context provided:

### Prognosis:
- Mutated IGHV Gene: Generally associated with a better prognosis. People with this mutation often have more effective treatment responses and longer survival rates.
- 13q Deletion: This is considered a favorable prognostic factor, indicating a better outlook.
- Elevated LDH: High levels of lactate dehydrogenase (LDH) can be a sign of more aggressive disease, which might affect the prognosis negatively.

### Treatment:
- Favorable Prognostic Factors: With mutated IGHV and 13q deletion, you might have a better response to treatment and potentially longer periods of remission.
- Elevated LDH: This might prompt your doctor to consider more aggressive treatment options to manage the disease effectively.

Your doctor will use these factors to tailor a treatment plan that best fits your specific situation.

May 26, 2024

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