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Real members of MyLeukemiaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Is deletion 17p (TP53 locus) ABSENT the same as 17p deletion? I have early stage CLL

A MyLeukemiaTeam Member asked a question 💭
Ottawa, ON
July 26, 2024
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A MyLeukemiaTeam Member

Hi Roberta2,
I have not had this testing done yet, so I know nothing about the genetics of having CLL.
Stay in touch with people on this site so you have some support. I will be praying 🙏 for you that your type of leukemia is not aggressive.🙂 Good luck!🍀

July 26, 2024
MyLeukemiaTeam

Yes, "deletion 17p (TP53 locus) absent" means that the 17p deletion is not present. In the context of chronic lymphocytic leukemia (CLL), the presence of a 17p deletion, which includes the TP53 gene, is associated with a more aggressive disease and may require more urgent treatment. If this deletion is absent, it generally Show Full Answer

Yes, "deletion 17p (TP53 locus) absent" means that the 17p deletion is not present. In the context of chronic lymphocytic leukemia (CLL), the presence of a 17p deletion, which includes the TP53 gene, is associated with a more aggressive disease and may require more urgent treatment. If this deletion is absent, it generally indicates a better prognosis.

For early-stage CLL, the absence of the 17p deletion is a favorable sign. However, it's important to continue regular monitoring and follow your doctor's recommendations.

July 26, 2024
A MyLeukemiaTeam Member

Hi Roberta2, confusing isn’t it! I asked my hematology oncologist to explain it to me. She’s awesome and helped make it easier for me to understand so I stopped worrying about it. Peace and prayers, Christine

July 26, 2024
A MyLeukemiaTeam Member

Amen

July 27, 2024

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