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Real members of MyLeukemiaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
August 8, 2025
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A MyLeukemiaTeam Member

I have droopy eyelids which and eye doctor told me he could recommend plastic surgery to fix? I have noticed my father has the same type of eye lid problem so it may not be an ill affect from my illness? My other "skin" affect is when I exercise or jog my leg below the knee will change color from bursting capillaries in the skin. I have seen pink, reddish, purple skin colors to my ankle. After a few days of not exercising the skin returns to normal.

August 8, 2025
MyLeukemiaTeam

Yes, skin-related side effects are common with TKI medications like Gleevec. Many MyLeukemiaTeam members have reported experiencing itchy skin while taking CML treatments. Both targeted therapy and chemotherapy can cause dry, itchy skin as a side effect.

Here are some tips to help manage skin-related side effects
• Use Show Full Answer

Yes, skin-related side effects are common with TKI medications like Gleevec. Many MyLeukemiaTeam members have reported experiencing itchy skin while taking CML treatments. Both targeted therapy and chemotherapy can cause dry, itchy skin as a side effect.

Here are some tips to help manage skin-related side effects:
• Use gentle, soap-free cleansers
• Apply moisturizer frequently
• Use sunscreen when outdoors
• Stay out of direct sunlight when possible
• Talk to your doctor about additional treatments or medications that may help Remember that everyone reacts differently to CML medications - you may experience different or more severe side effects than others taking the same treatment. If your side effects become too difficult to manage, don't stop taking your medication without consulting your doctor first. They can help adjust your treatment plan, potentially by changing your dosage or switching to a different TKI medication that may work better for you.

August 8, 2025

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