What are the typical first-line medications for CML?
Tyrosine kinase inhibitors (TKIs) are the standard first-line treatment for chronic myeloid leukemia (CML). These targeted therapies block the abnormal proteins that help cancer cells grow and divide.
The most commonly prescribed TKIs for newly diagnosed CML include:
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What are the typical first-line medications for CML?
Tyrosine kinase inhibitors (TKIs) are the standard first-line treatment for chronic myeloid leukemia (CML). These targeted therapies block the abnormal proteins that help cancer cells grow and divide.
The most commonly prescribed TKIs for newly diagnosed CML include:
* Imatinib (Gleevec)
* Nilotinib (Tasigna or Danziten)
* Dasatinib (Sprycel)
* Bosutinib (Bosulif)
* Asciminib (Scemblix)
Imatinib was the first TKI approved and has been used successfully for many years. Almost all people with CML respond well to it. The newer TKIs like nilotinib, dasatinib, and asciminib may also be used as initial treatment options.
Your doctor will choose which TKI is best for you based on your specific situation, the phase of your CML, and any other health factors. These medications are typically taken daily as tablets or capsules at home.
February 5
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