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Real members of MyLeukemiaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I am inquiring about the current research initiatives focused on potential cures for Chronic Lymphocytic Leukemia (CLL). Does the platform provide its members with consistent updates regarding treatments that are in various stages of clinical trials? While I possess knowledge of functional treatments and options, I am specifically interested in information pertaining to potential cures. Furthermore, does this platform elucidate the phases of the ongoing trials for CLL and other hematological… read more

May 14
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A MyLeukemiaTeam Member

I have heard and read about taking two different medications to control those bad cells. I think this is a good idea and it should be given to more people. I take Brukinsa and I had read the medication is now effective for 10 to 20 years or a failure rate of 4% per year. I just changed my medication to 50% dose and my blood tests indication 100% normal with a WBC count of 7,600. I think the original dose of 320 mg may have been a super dose to really attack those bad cells quickly. I think we experiment with our body it we do nothing or if we do something that effects our health. We have the choice of doing research to find answers so we can make the right choice to help our health. Celebrating Long Life (CLL)

May 14
MyLeukemiaTeam

What a great set of questions! Here's what's known about CLL clinical trials and the pursuit of a cure.

Clinical trials are research studies that help determine whether new treatments are safe and effective. Participating in a trial may give access to cutting-edge medications not yet widely available. Speaking with a Show Full Answer

What a great set of questions! Here's what's known about CLL clinical trials and the pursuit of a cure.

Clinical trials are research studies that help determine whether new treatments are safe and effective. Participating in a trial may give access to cutting-edge medications not yet widely available. Speaking with a hematologist or oncologist is the best first step to finding trials that match a specific situation. Regarding potential cures, a curative approach is generally considered for younger, healthier patients and typically involves more aggressive treatment strategies. Current research is heavily focused on targeted therapies and combinations, including:

- BTK inhibitors like ibrutinib, acalabrutinib, and zanubrutinib
- BCL-2 inhibitors like venetoclax
- CAR-T cell therapy, where a patient's own immune cells are modified to attack leukemia cells
- Allogeneic bone marrow transplant, which remains one of the closest options to a cure for eligible patients For the most up-to-date clinical trial phases and research initiatives, ClinicalTrials.gov is an excellent resource. Organizations like the Leukemia & Lymphoma Society and American Cancer Society also provide regularly updated information on emerging CLL treatments and trial phases.

Always consult with a specialist before making any treatment decisions — they can help match specific circumstances to the most relevant and promising options available.

May 14

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