Yes, people with chronic myeloid leukemia (CML) do face a higher risk of developing a second cancer. In fact, CML patients are 30% to 50% more likely to be diagnosed with another cancer compared to the general population. The types of second cancers most associated with CML include:
- Lung cancer
- Thyroid cancer
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Yes, people with chronic myeloid leukemia (CML) do face a higher risk of developing a second cancer. In fact, CML patients are 30% to 50% more likely to be diagnosed with another cancer compared to the general population. The types of second cancers most associated with CML include:
- Lung cancer
- Thyroid cancer
- Melanoma (a type of skin cancer)
- Prostate cancer
- Cancer of the mouth
- Cancer of the small intestines
- Chronic lymphocytic leukemia (CLL) There are a few reasons why this increased risk exists. CML treatments, including certain targeted therapies like tyrosine kinase inhibitors (TKIs), can suppress the immune system, making it harder for the body to fight off abnormal cells that could become cancerous.
Leukemia itself may also play a role — even before treatment begins — possibly by disrupting the immune system's ability to destroy damaged or abnormal cells. It's worth noting that second cancers, when they do occur, most often appear between 5 and 10 years after the initial leukemia diagnosis. Not every CML patient will develop a secondary cancer, but staying on top of regular screenings and check-ups with a doctor is really important for catching anything early.
A MyLeukemiaTeam member with CLL shared a helpful tip that applies broadly: "Try to avoid skin cancer! I have had many since I got CLL. Our immune systems do nothing to prevent them!" — a good reminder to take sun protection seriously and report any unusual skin changes to a doctor promptly.
May 19
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