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A MyLeukemiaTeam Member asked a question 💭
Australia
February 23
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Can bone marrow results show how far the leukemia has progressed in CMML-1?

Yes, bone marrow results are essential for understanding the stage of CMML. The bone marrow biopsy and aspiration help doctors measure specific markers that indicate disease progression.

For CMML specifically, doctors look at
* The percentage of Show Full Answer

Can bone marrow results show how far the leukemia has progressed in CMML-1?

Yes, bone marrow results are essential for understanding the stage of CMML. The bone marrow biopsy and aspiration help doctors measure specific markers that indicate disease progression.

For CMML specifically, doctors look at:
* The percentage of blast cells (immature cells) in the bone marrow
* Levels of monocytes and other blood cells
* Any genetic or chromosome changes

The "1" in CMML-1 means your dad has fewer than 5% blasts in his blood and fewer than 10% blasts in his bone marrow. This indicates he's in an earlier phase of the disease.

If blast levels increase to 10-19% in the bone marrow, it would be classified as CMML-2. Having more than 20% blasts would indicate progression to acute leukemia.

Doctors also use bone marrow samples for cytogenetic and molecular tests to identify specific gene changes. These results help determine prognosis and guide treatment decisions.

It's important to note that CMML requires multiple abnormal test results over time for diagnosis, as other conditions can temporarily affect blood cell levels.

February 23

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