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A MyLeukemiaTeam Member asked a question 💭
Miami, FL
April 22
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A MyLeukemiaTeam Member

I take Brukinsa which is a BTK inhibitor. My blood tests have all been 100% normal and my WBC count has been 7,500. I am active and visit the gym 3 times a week and do activities at my property. I just learned from a new doctor who reviewed my medical record my spleen is enlarged? I never had any lumps or bumps from excess WBC? I hope you find your answer to your question so you can decide your next step?

April 22
A MyLeukemiaTeam Member

Hi JesusRodriguez,

My knowledge of remission came through my routine bloodwork. When I was diagnosed there was no talk of remission for me. The best I could do was a flat line of the bcr/abl. I achieved that after a few years of treatment but still stayed on my drug (TKI) for 2 years more, I believe. Then they took me off the TKI to see how I did. They told me later that if my CML was to return the bcr/abl usually spikes within 6 months after discontinuing the TKI. I have had only one bone marrow aspiration and that was to confirm my diagnosis of the type of Leukemia I had. I continue to have blood work done routinely, I stay in touch with my doc but only see him 1 X a year now. But, and this is important if my blood work starts to tank (and it can) we start treatment immediately. This is my story and what I know of this treatment--your doctor may do things differently. Wishing you the best outcome possible.--jmb

April 22
MyLeukemiaTeam

How long after starting tyrosine kinase inhibitors can remission testing be repeated?

The timing for remission testing after starting tyrosine kinase inhibitors (TKIs) isn't specifically detailed in the available information. However, what we do know is that achieving remission is a gradual process that requires consistent Show Full Answer

How long after starting tyrosine kinase inhibitors can remission testing be repeated?

The timing for remission testing after starting tyrosine kinase inhibitors (TKIs) isn't specifically detailed in the available information. However, what we do know is that achieving remission is a gradual process that requires consistent medication adherence.

For chronic myeloid leukemia (CML), remission is typically defined by having less than 5 percent blast cells in the bone marrow and blood cell counts returning to normal levels. The goal of TKI therapy is to minimize leukemia cells and achieve this complete hematologic response.

Your hematology/oncology doctor will determine the appropriate schedule for monitoring your response to treatment. They'll use blood tests and possibly bone marrow biopsies to check how well the medication is working.

It's important to take your TKI exactly as prescribed - at the same time every day, following any fasting requirements, and never skipping doses. Adherence is critical for achieving the best possible response to treatment.

If you have questions about when your next remission test will be scheduled, talk to your doctor. They can explain the monitoring plan specific to your situation and treatment goals.

April 22

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