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Real members of MyLeukemiaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I’m on wait and watch. I was diagnosed about a year ago.

May 27
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MyLeukemiaTeam

Has anyone else with CMML-2 experienced a sudden rise in iron levels along with extreme exhaustion?

Yes, changes in blood levels — including iron — can happen with CMML, and fatigue is one of the most commonly reported symptoms. Other MyLeukemiaTeam members have shared similar experiences of sudden shifts in how they feel Show Full Answer

Has anyone else with CMML-2 experienced a sudden rise in iron levels along with extreme exhaustion?

Yes, changes in blood levels — including iron — can happen with CMML, and fatigue is one of the most commonly reported symptoms. Other MyLeukemiaTeam members have shared similar experiences of sudden shifts in how they feel, especially during the watch-and-wait phase. With CMML-2, the bone marrow isn't producing healthy blood cells properly. This can throw off many things in the body, including iron regulation. Elevated iron can actually contribute to fatigue on its own, so combined with CMML, it's understandable that exhaustion feels more intense right now.

It's really important to flag this change to your care team as soon as possible. Even on watch-and-wait, new or worsening symptoms — especially extreme fatigue — are worth reporting. They may want to:

- Recheck your full blood count
- Monitor your iron levels more closely
- Reassess whether watch-and-wait is still the right approach for you

You're not imagining it — this is your body telling you something has shifted, and your doctor needs to know.

May 27

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